货号价格

CDL-HM427F-100μg / 询价

CDL-HM427F-500μg / 询价

CDL-HM427F-500μgx2 / 询价

FITC-Labeled Human CD27 Ligand/CD70 Trimer Protein

产品信息(Product Info)
表达区间及表达系统(Source)

Recombinant FITC-Labeled Human CD27 Ligand/CD70 Trimer Protein is expressed from HEK293 with His tag at the N-Terminus. It contains Leu50-Pro193.[Accession | P32970-1]

分子量大小(Molecular Weight)

The protein has a predicted MW of 51.8 kDa. Due to glycosylation, the protein migrates to 63-68 kDa based on Tris-Bis PAGE result.

波长(Wavelength)

Excitation Wavelength: 490 nm

Emission Wavelength: 520 nm

内毒素(Endotoxin)

Less than 1EU per μg by the LAL method.

纯度(Purity)

> 95% as determined by Tris-Bis PAGE

制剂(Formulation)

Supplied as 0.22μm filtered solution in PBS (pH 7.4).

存储(Storage)

Valid for 12 months from date of receipt when stored at -80°C.
Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

产品数据(Assay Data)
Tris-Bis PAGE

FITC-Labeled Human CD27 Ligand Trimer on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

背景(Background)

CD70, also named CD27 ligand (CD27L), is a type II transmembrane glycoprotein belonging to the TNF superfamily (TNFSF) and has been designated TNFSF7.  CD70 is a cytokine that binds to CD27. Plays a role in T-cell activation. Induces the proliferation of costimulated T-cells and enhances the generation of cytolytic T-cells.

分子别名(Synonyms)

CD70 molecule; CD70; TNFSF7; CD27 Ligand; CD27-L; CD27LG; Ki-24 antigen; TNFSF7G

文献(References)

(1)Buchan S L , Rogel A , Al-Shamkhani A. The immunobiology of CD27 and OX40 and their potential as targets for cancer immunotherapy[J]. Blood, 2017:blood-2017-07-741025.